Protoplasm, term once used to describe the ground substance—the living material—of cells. This material would include the complex colloidal organization of substances making up a cell's nucleus, cytoplasm, plastids, and mitochondria. The term protoplasm has to a great extent been replaced by the term cytoplasm; the latter, however, does not include the cell nucleus. Protoplasm is also used to describe the contents of the tubelike structures (hyphae) of which fungi are composed.
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